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Despicable Me
2010
This page collects YouTube reaction videos for Despicable Me — first-time watches, commentaries, and reactor opinions all in one place. Subscribe to get notified when new reactions drop.
Reactions (7)
Despicable Me (2010) | *First Time Watching* | Movie Reaction I Asia and BJ
Reelin' with Asia and BJ
55,901 views★0.00 (3,135 ratings)
1/12/2026
First time watching Despicable Me movie reaction
Badd Medicine
316,096 views★0.00 (14,116 ratings)
10/23/2024
It's so Fluffy !!! Despicable Me (2010) | FIRST TIME WATCHING
BissFlix
30,952 views★0.00 (2,082 ratings)
9/8/2024
*DESPICABLE ME* (2010) | First Time Watching | Movie Reaction
Mr FLICKS
30,453 views★0.00 (1,834 ratings)
2/27/2024
FIRST TIME WATCHING *Despicable Me*
SebScreen
495,940 views★0.00 (20,023 ratings)
10/11/2023
Despicable Me | Canadian First Time Watching | Movie Reaction | Movie Review | Movie Commentary
CineBinge
185,345 views★0.00 (8,095 ratings)
1/4/2023
DESPICABLE ME (2010) TWIN BROTHERS FIRST TIME WATCHING MOVIE REACTION!
OctoKrool
182,895 views★0.00 (6,543 ratings)
7/12/2022