Megamind

2010

🏆100K ClubReactions to this title usually perform well — 100K+ average views across many reactions.

This page gathers all 29 YouTube reaction videos for Megamind (2010) in one place — first-time watches, commentaries, and reactor opinions from creators across YouTube. No more searching channel by channel. Subscribe to follow this movie and we'll surface new reactions in your feed as they're published.

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Reactions (29)

Watching MEGAMIND For The First Time Turned Me Blue And Bald 🔵🧑‍🦲 (Movie Reaction)

Rukiya Reacts

192,360 views★5.00 (11,005 ratings)

6/28/2026

👽Cheers to the “bad guy”! 😈 Megamind | Movie Reaction

funnylilgalreacts

75,320 views★0.00 (4,751 ratings)

4/25/2026

MEGAMIND (2010) MOVIE REACTION - A PERFECT SUPERHERO FILM!? MOM & DAUGHTER FIRST TIME WATCHING!

Mama's Geeky

15,992 views★0.00 (839 ratings)

2/28/2026

CRIMINALLY UNDERRATED Megamind (2010) Reaction: FIRST TIME WATCHING

Nick Reacts

19,742 views★0.00 (1,426 ratings)

12/17/2025

💥MEGAMIND is HILARIOUS!!💥First Time Watching MOVIE REACTION

Jen Murray

25,526 views★0.00 (2,297 ratings)

11/24/2025

MEGAMIND (2010) MOVIE REACTION – THE GREATEST VILLAIN TURNED HERO! – FIRST TIME WATCHING – REVIEW

The Media Knights

422,107 views★0.00 (18,139 ratings)

9/9/2025

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Megamind (2010) | First Time Movie Reaction

Diegesis

181,737 views★0.00 (8,000 ratings)

9/6/2025

MEGAMIND BLEW MY MIND 🤯 | First Time Watching

MR. VIDEO CLIPS

78,172 views★0.00 (5,132 ratings)

8/27/2025

Filmmaker reacts to Megamind (2010) for the FIRST TIME!

James VS Cinema

21,669 views★0.00 (1,575 ratings)

6/6/2025

MEGAMIND (2010) | Movie REACTION! | First Time Watch! | Dreamworks'

Galaxy Geeks

40,407 views★0.00 (1,235 ratings)

5/12/2025

MEGAMIND is better than DESPICABLE ME

Alex Hefner's TV & Movie Vault

482,057 views★0.00 (29,847 ratings)

5/2/2025

Villagers Watch Megamind for the First Time | Hilarious Reactions!

React 2.0

3,451 views★0.00 (206 ratings)

4/24/2025

MEGAMIND is mega FUN!! | First Time Reaction!

Addie Counts

39,751 views★0.00 (2,890 ratings)

3/7/2025

Megamind (2010) | First Time Watching | Movie Reaction | Asia and BJ

Reelin' with Asia and BJ

45,563 views★0.00 (2,621 ratings)

3/2/2025

First time watching MEGAMIND! How did I miss this?! | Movie React & Commentary

eyesondale

36,365 views★0.00 (2,468 ratings)

1/6/2025

MEGAMIND (2010) MOVIE REACTION!! FIRST TIME WATCHING!! Will Ferrell | Brad Pitt | Movie Review

Reel Rejects

252,400 views★0.00 (9,480 ratings)

11/25/2024

My wife watches MEGAMIND for the FIRST time || Movie Reaction

Holden & Jen Hardman

84,394 views★0.00 (4,298 ratings)

8/21/2024

Megamind I First Time Reaction I Movie Review & Commentary

Reacts With Jax

104,199 views★0.00 (5,161 ratings)

2/16/2024

Megamind | First Time Watching | Movie Reaction | Movie Review | Movie Commentary

Dasha Reacts

19,007 views★0.00 (1,551 ratings)

1/31/2024

What a gem of a film!!! First time watching Megamind movie reaction

Badd Medicine

498,559 views★0.00 (22,115 ratings)

12/14/2023

Megamind is THE FUNNIEST ANIMATED MOVIE EVER!

VKunia

193,114 views★0.00 (10,429 ratings)

11/14/2023

Megamind | Canadian First Time Watching | Movie Reaction | Movie Review | Movie Commentary

CineBinge

201,882 views★0.00 (9,910 ratings)

1/13/2023

#Megamind may be the FUNNIEST animated movie EVER?!

Mary Cherry

153,306 views★0.00 (7,468 ratings)

11/25/2022

Megamind SLAPS! Movie Reaction & Review | First Time Watching

Dos Cavazos

239,458 views★0.00 (9,613 ratings)

8/7/2022

MEGAMIND (2010) TWIN BROTHERS FIRST TIME WATCHING MOVIE REACTION!

OctoKrool

228,708 views★0.00 (9,392 ratings)

5/11/2022

A HIDDEN CLASSIC!! Megamind (2010) Reaction: FIRST TIME WATCHING

Nick Reacts

128,540 views★0.00 (6,952 ratings)

4/16/2022

MEGAMIND (2010) | FIRST TIME WATCHING | MOVIE REACTION

Mr FLICKS

21,909 views★0.00 (936 ratings)

3/27/2022

MEGAMIND (2010) is a MASTERPIECE! Movie Reaction

PUGGA

42,687 views★0.00 (1,777 ratings)

2/19/2022

FIRST TIME WATCHING MEGAMIND Movie Reaction!

SebScreen

231,706 views★0.00 (9,934 ratings)

11/11/2021

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This page collects every indexed YouTube reaction for Megamind (2010) in one place — first-time watches, commentaries, and reactor opinions. Just pick a video below and watch.

How many reactions are there for Megamind?

We currently track 29 reaction videos for Megamind, and the list grows as new reactions are published.

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